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Human DLL1 / Delta-like 1 (His Tag) recombinant protein

Cat.#: 501091

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Product Information

  • Product Name
    Human DLL1 / Delta-like 1 (His Tag) recombinant protein
  • Documents
  • Description
    Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.
  • Protein name
    Delta-like protein 1
  • Protein short names
    DELTA1; H-DELTA-1; DELTA; DL1; DLL1
  • Uniprot ID
    O00548
  • Gene Name
    DLL1; UNQ146/PRO172
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human DLL1 (NP_005609.3) extracellular domain (Met 1-Gly 540) was fused with a polyhistidine tag at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human DLL1 consists of 530 amino acids and predictes a molecular mass of 57.4 kDa. In SDS-PAGE under reducing conditions, rh DLL1 migrates as an approximately 58 kDa band due to glycosylation.
  • Purity
    > 98 % as determined by SDS-PAGE
  • Activity
    1. Measured by its ability to bind human NOTCH1 in a functional ELISA.
    2. Measured by the ability of the immobilized protein to enhance BMP2 induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 2-20 μg/mL.
  • Validations

    Human DLL1 / Delta-1 Protein (His Tag) SDS-PAGE

    Human DLL1 / Delta-1 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"