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  • DEDD Polyclonal Antibody
  • DEDD Polyclonal Antibody
  • DEDD Polyclonal Antibody

DEDD Polyclonal Antibody

Cat.#: 166633

Special Price 174.2 USD

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Product Information

  • Product Name
    DEDD Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to DEDD
  • Tested applications
    WB, IHC
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    DEDD antibody; CASP8IP1 antibody; DEDD1 antibody; DEFT antibody; FLDED1 antibody; KE05 antibody; death effector domain containing antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-318 of human DEDD (NP_001034801.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
    IHC 1:50 - 1:100
  • Validations

    Immunohistochemistry - DEDD Polyclonal Antibody

    Immunohistochemistry - DEDD Polyclonal Antibody

    Immunohistochemistry of paraffin-embedded rat lung using DEDD antibody at dilution of 1:100 (40x lens).

    Immunohistochemistry - DEDD Polyclonal Antibody

    Immunohistochemistry - DEDD Polyclonal Antibody

    Immunohistochemistry of paraffin-embedded human esophagus using DEDD antibody at dilution of 1:100 (40x lens).

    Immunohistochemistry - DEDD Polyclonal Antibody

    Immunohistochemistry - DEDD Polyclonal Antibody

    Immunohistochemistry of paraffin-embedded mouse kidney using DEDD antibody at dilution of 1:100 (40x lens).

  • Background
    A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity).
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"