DCLK1 antibody

DCLK1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

DCLK1 Rabbit Polyclonal antibody. Positive WB detected in rat brain tissue, human brain tissue, mouse brain tissue. Observed molecular weight by Western-blot: 48 kDa,82 kDa

ELISA, WB

Human,Mouse,Rat; other species not tested.

DCAMKL1 antibody; DCDC3A antibody; DCLK antibody; DCLK1 antibody; doublecortin like kinase 1 antibody; KIAA0369 antibody

Rabbit IgG

This antibody was obtained by immunization of DCLK1 recombinant protein (Accession Number: NM_004734). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

DCLK1(Serine/threonine-protein kinase DCLK1) is also named as DCAMKL1, DCDC3A, KIAA0369 and belongs to the CAMK Ser/Thr protein kinase family. It is a microtubule-associated kinase that can undergo autophosphorylation and it also has microtubule-polymerizing activity that is independent of its protein kinase activity(PMID:11124993). It plays a unique role in mitotic spindle integrity during early neurogenesis in radial glial cell proliferation and their radial process stability. DCLK1 is a unique marker for distinguishing tumor stem cells from intestinal normal stem cells(PMID:23202126). This protein has 4 isoforms produced by alternative splicing with the molecular weight of 82 kDa, 81 kDa,47 kDa and 48 kDa.