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Human ACO1/irp1 (His Tag) recombinant protein

Cat.#: 501341

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Product Information

  • Product Name
    Human ACO1/irp1 (His Tag) recombinant protein
  • Documents
  • Description
    Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding.
  • Protein name
    Cytoplasmic aconitate hydratase
  • Protein short names
    RP23-9F23.1; RP11-334P12.1; IRP1; ACO-1; IREB1; IREBP; IREBP1; AI256519; HEL60; ACONS
  • Uniprot ID
    P21399
  • Gene Name
    ACO1; IREB1
  • Source/Expression Host
    Baculovirus-Insect Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human ACO1 (P21399) (Met 1-Lys 889) was expressed, with a polyhistidine tag at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human ACO1 consists of 908 amino acids and has a calculated molecular mass of 101 kDa. It migrates as an approximately 90 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Validations

    Human ACO1 / irp1 Protein (His Tag) SDS-PAGE

    Human ACO1 / irp1 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"