Cytokeratin 19-specific antibody

Cytokeratin 19-specific antibody

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Cytokeratin 19-specific Rabbit Polyclonal antibody. Positive IHC detected in human colon tissue, human appendix tissue, human breast cancer tissue, human cervix tissue, human endometrial cancer tissue, human kidney tissue, human liver cancer tissue, human lung cancer tissue, human lung tissue, human ovary tumor tissue, human pancreas tissue, human placenta tissue, human prostate cancer tissue, human prostate hyperplasia tissue, human skin tissue, human stomach cancer tissue, human testis tissue, human thyroid cancer tissue. Positive WB detected in HepG2 cells. Observed molecular weight by Western-blot: 40 kDa

ELISA, WB, IHC

Human; other species not tested.

CK 19 antibody; CK19 antibody; Cytokeratin 19 antibody; K19 antibody; K1CS antibody; keratin 19 antibody; KRT19 antibody

Rabbit IgG

This antibody was obtained by immunization of Peptide (Accession Number: NM_002276). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. Keratin 19 is a type I cytokeratin. It is a biochemical marker of skin stem cells in vivo and in vitro. This antibody is specifically against KRT19.

• Kapoor A, Yao W, Ying H. Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer. Cell. 158(1):185-97. 2014.