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Cytokeratin 19 antibody

Cat.#: 107232

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Special Price 239.0 USD

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Product Information

  • Product Name
    Cytokeratin 19 antibody
  • Documents
  • Description
    Cytokeratin 19 Mouse Monoclonal antibody. Positive IHC detected in human stomach cancer tissue, human breast cancer tissue, human kidney tissue, human liver cancer tissue, human skin tissue. Positive WB detected in MCF-7 cells, HepG2 cells. Observed molecular weight by Western-blot: 48 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    CK 19 antibody; CK19 antibody; Cytokeratin 19 antibody; K19 antibody; K1CS antibody; keratin 19 antibody; KRT19 antibody
  • Isotype
    Mouse IgG2b
  • Preparation
    This antibody was obtained by immunization of Cytokeratin 19 recombinant protein (Accession Number: NM_002276). Purification method: Protein A purified.
  • Clonality
    Monoclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:50-1:500

  • Validations

    MCF-7 cells were subjected to SDS PAGE followed by western blot with Catalog No:107232(KRT19 Antibody) at dilution of 1:1500

    MCF-7 cells were subjected to SDS PAGE followed by western blot with Catalog No:107232(KRT19 Antibody) at dilution of 1:1500

    Immunohistochemistry of paraffin-embedded human stomach cancer tissue slide using Catalog No:107232(KRT19 Antibody) at dilution of 1:200 (under 10x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

    Immunohistochemistry of paraffin-embedded human stomach cancer tissue slide using Catalog No:107232(KRT19 Antibody) at dilution of 1:200 (under 10x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

    Immunohistochemistry of paraffin-embedded human stomach cancer tissue slide using Catalog No:107232(KRT19 Antibody) at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

    Immunohistochemistry of paraffin-embedded human stomach cancer tissue slide using Catalog No:107232(KRT19 Antibody) at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

  • Background
    The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. KRT19, one of type I keratins, is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Due to its high sensitivity, KRT19 is the most used marker for detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. This antibody, generated against full length KRT19 protein, also recognizes KRT17, another type I keratin homologous to KRT19. KRT17 is used as a marker for trauma.
  • References
    • Pan QZ, Pan K, Wang QJ. Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells. Stem cells (Dayton, Ohio). 33(2):354-66. 2015.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"