Cytokeratin 18 antibody

Cytokeratin 18 antibody

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• Material Safety Data Sheets (MSDS)

Cytokeratin 18 Rabbit Polyclonal antibody. Positive IF detected in MCF-7 cells. Positive IHC detected in human breast cancer tissue, human cervical cancer tissue, human colon cancer tissue, human endometrial cancer tissue, human liver cancer tissue, human liver tissue, human lung cancer tissue, human nephroblastoma tissue, human oesophagus cancer tissue, human ovary tumor tissue, human prostate cancer tissue, human skin cancer tissue. Positive WB detected in A431 cells, HepG2 cells. Positive IP detected in A431 cells. Observed molecular weight by Western-blot: 48 kDa

ELISA, WB, IF, IHC, IP

Human,Mouse,Rat; other species not tested.

CK 18 antibody; CYK18 antibody; Cytokeratin 18 antibody; K18 antibody; keratin 18 antibody; KRT18 antibody

Rabbit IgG

This antibody was obtained by immunization of Peptide (Accession Number: NM_000224). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT18, also named as CYK18, PIG46 and K18, is the most commonly found members of the intermediate filament gene family. KRT18 is a type I keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas. This antibody is specifically agianst KRT18.