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Product Name
Mouse Cystatin C / CST3 (His Tag) recombinant protein
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Description
As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity.
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Protein name
Cystatin-C
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Protein short names
RP23-250M11.9; MGC117328; CYSC; ARMD11; CST3; CYSTATIN C
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Uniprot ID
P21460
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Gene Name
Cst3
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse CST3 (NP_034106.2) precursor (Met 1-Ala 140) was expressed with a C-terminal polyhistidine tag.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse CST3 consists of 131 amino acids and has a calculated molecular mass of 15 kDa. The recombinant protein migrates as three bands (15, 18 & 21-24 kDa) in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Activity
Measured by its ability to inhibit papain cleavage of a fluorogenic peptide substrate Z-FR-AMC,R&D Systems, Catalog # ES009. The IC50 value is < 10 nM.
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Validations
Mouse Cystatin C / CST3 Protein (His Tag) SDS-PAGE
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