-
Product Name
CYP51A1 antibody
- Documents
-
Description
CYP51A1 Rabbit Polyclonal antibody. Positive IP detected in mouse testis tissue. Positive WB detected in PC-3 cells, HL-60 cells, mouse kidney tissue, mouse lung tissue, mouse ovary tissue, mouse testis tissue. Observed molecular weight by Western-blot: 57kd
-
Tested applications
ELISA, WB, IP
-
Species reactivity
Human,Mouse,Rat; other species not tested.
-
Alternative names
CP51 antibody; CYP51 antibody; CYP51A1 antibody; CYPL1 antibody; CYPLI antibody; CytOChrome P450 14DM antibody; CytOChrome P450 51A1 antibody; CytOChrome P45014DM antibody; CytOChrome P450LI antibody; LDM antibody; P450 14DM antibody; P450L1 antibody; Sterol 14 alpha demethylase antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of CYP51A1 recombinant protein (Accession Number: NM_000786). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:500-1:5000
-
Validations
PC-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:109711(CYP51A1 antibody) at dilution of 1:1000
IP Result of anti-CYP51A1 (IP:Catalog No:109711, 4ug; Detection:Catalog No:109711 1:1000) with mouse testis tissue lysate 2800ug.
-
Background
CYP51A1 represents cytochrome P450, family 51, subfamily A, polypeptide 1
-
References
- Porter TD, Banerjee S, Stolarczyk EI, Zou L. Suppression of cytochrome P450 reductase (POR) expression in hepatoma cells replicates the hepatic lipidosis observed in hepatic POR-null mice. Drug metabolism and disposition: the biological fate of chemicals. 39(6):966-73. 2011.
- Xu T, Zheng L, Xu L. Protective effects of dioscin against alcohol-induced liver injury. Archives of toxicology. 88(3):739-53. 2014.
- Bruce A, Rybak AP. CYB5D2 requires heme-binding to regulate HeLa cell growth and confer survival from chemotherapeutic agents. PloS one. 9(1):e86435. 2014.
- Head SA, Shi W, Zhao L. Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 112(52):E7276-85. 2015.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"