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Product Name
CYP2C19 Polyclonal Antibody
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Description
Polyclonal antibody to CYP2C19
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Tested applications
WB, IHC, IF
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Species reactivity
Human
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Alternative names
CYP2C19 antibody; CPCJ antibody; CYP2C antibody; CYPIIC17 antibody; CYPIIC19 antibody; P450C2C antibody; P450IIC19 antibody; cytochrome P450 2C19 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human CYP2C19
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, pH7.3.
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Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:1000
IHC 1:50 - 1:100
IF 1:20 - 1:50 -
Validations
Western blot - CYP2C19 Polyclonal Antibody
Western blot analysis of extracts of HL-60 cells, using CYP2C19 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Background
Responsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram and imipramine. Oxygenates (R)- and (S)-limonene to produce carveol and perillyl alcohol. Hydroxylates fenbendazole at the 4' position.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"