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Product Name
CYP2A6 Polyclonal Antibody
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Description
Polyclonal antibody to CYP2A6
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Tested applications
WB, IF
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Species reactivity
Human, Mouse, Rat
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Alternative names
CYP2A6 antibody; CPA6 antibody; CYP2A antibody; CYP2A3 antibody; CYPIIA6 antibody; P450C2A antibody; P450PB antibody; cytochrome P450 2A6 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 91-300 of human CYP2A6 (NP_000753.3).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IF 1:50 - 1:200 -
Validations
Immunofluorescence - CYP2A6 Polyclonal Antibody
Immunofluorescence analysis of HeLa cells using CYP2A6 antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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Background
Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"