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Product Name
Human CDKN2D/p19ink4d (GST Tag) recombinant protein
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Description
Interacts strongly with CDK4 and CDK6 and inhibits them.
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Protein name
Cyclin-dependent kinase 4 inhibitor D
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Protein short names
P19INK4D; P19-INK4D; INK4D; P19
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Uniprot ID
P55273
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Gene Name
CDKN2D
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human CDKN2D (P55273) (Met 10Leu 166) was fused with the GST tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CDKN2D/GST chimera consists of 400 amino acids and has a predicted molecular mass of 44.9 kDa. It migrates as an approxiamtely 46 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Activity
Immobilized human GST-CDKN2D at 10 μg/ml (100 μl/well) can bind biotinylated human GST-CDK4 (Cat:501272), The EC50 of biotinylated human GST-CDK4 (Cat:501272) is 0.52-1.2 μg/ml.
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Validations
Human CDKN2D / p19ink4d Protein (GST Tag) SDS-PAGE
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