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Product Name
Human CDK16/PCTK1/PCTAIRE1 (GST Tag) recombinant protein
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Description
Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Regulates GH1 release by brain neurons. Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis. Regulates neuron differentiation and dendrite development (By similarity). Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Can phosphorylate CCNY at 'Ser-336' (in vitro).
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Protein name
Cyclin-dependent kinase 16
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Protein short names
FLJ16665; PCTK1; RP23-394F6.3; PCTGAIRE; PCTAIRE; CRK5; PCTAIRE1; CDK16
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Uniprot ID
Q00536
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Gene Name
CDK16; PCTAIRE1; PCTK1
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human PCTK1 (Q00536-1) (Met 1-Phe 496) was fused with the GST tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human PCTK1/GST chimera consists of 720 amino acids and has a predicted molecular mass of 82 kDa. It migrates as an approximately 73 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 82 % as determined by SDS-PAGE
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Activity
1. Measured by its ability to bind biotinylated human GST-EK-YWHAH (Cat:502438) in a functional ELISA.
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Validations
Human CDK16 / PCTAIRE1 / PCTK1 Protein (GST Tag) SDS-PAGE
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