CXCR7-Specific antibody

Cat.#: 109647

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Product Information

  • Product Name
    CXCR7-Specific antibody
  • Documents
  • Description
    CXCR7-Specific Rabbit Polyclonal antibody. Positive IHC detected in mouse brain tissue. Positive WB detected in K-562 cells, C6 cells, mouse brain tissue. Positive IP detected in K-562 cells. Observed molecular weight by Western-blot: 50 kDa
  • Tested applications
    ELISA, WB, IP, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    Chemokine orphan receptor 1 antibody; CMKOR1 antibody; CXC R7 antibody; CXCR 7 antibody; CXCR7 antibody; G protein coupled receptor 159 antibody; GPR159 antibody; RDC 1 antibody; RDC1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_020311). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:1000

    IP: 1:200-1:2000

    IHC: 1:50-1:500

  • Validations

    K-562 cells were subjected to SDS PAGE followed by western blot with Catalog No:109647(CXCR7-Specific antibody) at dilution of 1:100

    K-562 cells were subjected to SDS PAGE followed by western blot with Catalog No:109647(CXCR7-Specific antibody) at dilution of 1:100

    IP Result of anti-CXCR7-Specific (IP:Catalog No:109647, 4ug; Detection:Catalog No:109647 1:500) with K-562 cells lysate 3200ug.

    IP Result of anti-CXCR7-Specific (IP:Catalog No:109647, 4ug; Detection:Catalog No:109647 1:500) with K-562 cells lysate 3200ug.

    Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:109647(CXCR7-Specific Antibody) at dilution of 1:100 (under 10x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

    Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:109647(CXCR7-Specific Antibody) at dilution of 1:100 (under 10x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

    Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:109647(CXCR7-Specific Antibody) at dilution of 1:100 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

    Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:109647(CXCR7-Specific Antibody) at dilution of 1:100 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

  • Background
    CXCR7 (C-X-C chemokine receptor type 7), also known as RDC1, is a member of the G-protein coupled receptor family. CXCR7 can bind the chemokines CXCL11 and CXCL12 with high affinity, and it also acts as coreceptor with CXCR4 for a restricted number of HIV isolates. Expression of CXCR7 has been associated with cardiac development as well as with tumor growth and progression. This antibody is specific to CXCR7.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"