-
Product Name
CXCR7 antibody
- Documents
-
Description
CXCR7 Mouse Monoclonal antibody. Positive IHC detected in human breast cancer tissue. Positive WB detected in Jurkat cells. Observed molecular weight by Western-blot: 50 kDa
-
Tested applications
ELISA, WB, IHC
-
Species reactivity
Human,Mouse; other species not tested.
-
Alternative names
Chemokine orphan receptor 1 antibody; CMKOR1 antibody; CXC R7 antibody; CXCR 7 antibody; CXCR7 antibody; G protein coupled receptor 159 antibody; GPR159 antibody; RDC 1 antibody; RDC1 antibody
-
Isotype
Mouse IgG2b
-
Preparation
This antibody was obtained by immunization of CXCR7 recombinant protein (Accession Number: XM_047445135). Purification method: Protein G purified.
-
Clonality
Monoclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
-
Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:107188(CXCR7 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:107188(CXCR7 Antibody) at dilution of 1:200 (under 10x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using Catalog No:107188(CXCR7 Antibody) at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
-
Background
CXCR7 (C-X-C chemokine receptor type 7), also known as RDC1, is a member of the G-protein coupled receptor family. CXCR7 can bind the chemokines CXCL11 and CXCL12 with high affinity, and it also acts as coreceptor with CXCR4 for a restricted number of HIV isolates. Expression of CXCR7 has been associated with cardiac development as well as with tumor growth and progression.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"