CXCL8/IL8 antibody

CXCL8/IL8 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

CXCL8/IL8 Mouse Monoclonal antibody. Positive WB detected in ag10552. Observed molecular weight by Western-blot: 37 kDa

ELISA, WB

Human; other species not tested.

C X C motif chemokine 8 antibody; CXC chemokine ligand 8 antibody; CXCL 8 antibody; CXCL8 antibody; IL 8 antibody; IL8 antibody; Inteleukin 8 antibody; interleukin 8 antibody

Mouse IgG2a

This antibody was obtained by immunization of CXCL8/IL8 recombinant protein (Accession Number: NM_000584). Purification method: Protein A purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Interleukin 8 (IL-8), also known as CXCL8, which is a member of the CXC chemokine family. This chemokine is secreted by a variety of cell types including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, and various tumor cell lines in response to inflammatory stimuli. IL-8 has two primary functions. It induces chemotaxis in target cells, primarily neutrophils but also other granulocytes, causing them to migrate toward the site of infection. IL-8 also induces phagocytosis once they have arrived. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. IL-8 is also known to be a potent promoter of angiogenesis. IL-8 has been associated with tumor angiogenesis, metastasis, and poor prognosis in breast cancer. IL-8 may present a novel therapeutic target for estrogen driven breast carcinogenesis and tumor progression.

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