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  • CTNND1 Polyclonal Antibody
  • CTNND1 Polyclonal Antibody

CTNND1 Polyclonal Antibody

Cat.#: 166606

Special Price 174.2 USD

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Product Information

  • Product Name
    CTNND1 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to CTNND1
  • Tested applications
    WB, IF
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    CTNND1 antibody; CAS antibody; CTNND antibody; P120CAS antibody; P120CTN antibody; p120 antibody; p120 antibody; p120 antibody; catenin delta-1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 573-832 of human CTNND1 (NP_001078938.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
    IF 1:50 - 1:200
  • Validations

    Western blot - CTNND1 Polyclonal Antibody

    Western blot - CTNND1 Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using CTNND1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

    Immunofluorescence - CTNND1 Polyclonal Antibody

    Immunofluorescence - CTNND1 Polyclonal Antibody

    Immunofluorescence analysis of U2OS cells using CTNND1 antibody . Blue: DAPI for nuclear staining.

  • Background
    Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). Associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"