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CTBP2 antibody

Cat.#: 109625

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Product Information

  • Product Name
    CTBP2 antibody
  • Documents
  • Description
    CTBP2 Rabbit Polyclonal antibody. Positive IP detected in mouse heart tissue. Positive WB detected in mouse heart tissue. Observed molecular weight by Western-blot: 49 kDa
  • Tested applications
    ELISA, WB, IP
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    C terminal binding protein 2 antibody; CTBP2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of CTBP2 recombinant protein (Accession Number: XM_017015756). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IP: 1:200-1:2000

  • Validations

    mouse heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:109625(CTBP2 antibody) at dilution of 1:800

    mouse heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:109625(CTBP2 antibody) at dilution of 1:800

    IP Result of anti-CTBP2 (IP:Catalog No:109625, 4ug; Detection:Catalog No:109625 1:500) with mouse heart tissue lysate 3200ug.

    IP Result of anti-CTBP2 (IP:Catalog No:109625, 4ug; Detection:Catalog No:109625 1:500) with mouse heart tissue lysate 3200ug.

  • Background
    C-Terminal binding protein 2 (CTBP2) is a transcriptional repressor. It contains a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. This protein is thought to bind to the C-terminus of the adenovirus E1A proteins. Studies in mice suggested that this protein is involved in transcriptional repression. CTBP2 is expressed in all tissues tested, with a higher level of expression in the heart, skeletal muscle, and pancreas. The gene of CTBP2 is mapped to human chromosome 21q21.3.
  • References
    • Johnson SL, Forge A, Knipper M, Münkner S, Marcotti W. Tonotopic variation in the calcium dependence of neurotransmitter release and vesicle pool replenishment at mammalian auditory ribbon synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28(30):7670-8. 2008.
    • Du JT, Cao H, Zhou W. MicroRNA-200 family members are weakly expressed in the neurosensory epithelia of the developing zebrafish (Danio rerio) inner ear. Genetics and molecular research : GMR. 13(2):4187-201. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"