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Product Name
CTBP1 antibody
- Documents
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Description
CTBP1 Rabbit Polyclonal antibody. Positive IHC detected in human prostate cancer tissue. Positive WB detected in Jurkat cells, HeLa cells, HL-60 cells, mouse brain tissue, mouse skeletal muscle tissue, mouse thymus tissue. Positive IP detected in mouse brain tissue. Observed molecular weight by Western-blot: 48 kDa
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
BARS antibody; C terminal binding protein 1 antibody; CTBP antibody; CTBP1 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CTBP1 recombinant protein (Accession Number: NM_001328). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:1000
IHC: 1:20-1:200
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:109624(CTBP1 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:109624(CTBP1 antibody) at dilution of 1:50 (under 40x lens)
IP Result of anti-CTBP1 (IP:Catalog No:109624, 3ug; Detection:Catalog No:109624 1:200) with mouse brain tissue lysate 4000ug.
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Background
CTBP1, also named as C-terminal-binding protein 1, is a 440 amino acid protein, which belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. CTBP1 is a cellular phosphoprotein that associates with various proteins and functions as a corepressor of transcription. CTBP1 and the related protein CTBP2 are characterized as C-terminal binding protein of adenovirus E1A, and they preferentially associate with the E1A via a 5-amino acid motif, PLDLS, to repress E1A induced oncogenesis and cellular transformation. CTBP1 is expressed from embryo to adult, but CTBP2 is mainly expressed during embryogenesis.
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