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CRP antibody

Cat.#: 107177

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Product Information

  • Product Name
    CRP antibody
  • Documents
  • Description
    CRP Mouse Monoclonal antibody. Positive WB detected in serum from mouse injected with bacteria. Observed molecular weight by Western-blot: 27 kDa
  • Tested applications
    ELISA, WB
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    C reactive protein antibody; CRP antibody; PTX1 antibody
  • Isotype
    Mouse IgG2a
  • Preparation
    This antibody was obtained by immunization of CRP recombinant protein (Accession Number: NM_001329058). Purification method: Protein A purified.
  • Clonality
    Monoclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:1000-1:10000

  • Validations

    Serum from mouse injected with bacteria were subjected to SDS PAGE followed by western blot with Catalog No:107177 (CRP Antibody) at dilution of 1:2000. Horseradish peroxidase conjugated protein A was used for signal developing instead of secondary antibody.

    Serum from mouse injected with bacteria were subjected to SDS PAGE followed by western blot with Catalog No:107177 (CRP Antibody) at dilution of 1:2000. Horseradish peroxidase conjugated protein A was used for signal developing instead of secondary antibody.

    Serum from normal mouse (left) and mouse injected with bacteria (right) were subjected to SDS PAGE followed by western blot with Catalog No:107177 (CRP Antibody) at dilution of 1:500. Horseradish peroxidase conjugated protein A was used for signal developing instead of secondary antibody.

    Serum from normal mouse (left) and mouse injected with bacteria (right) were subjected to SDS PAGE followed by western blot with Catalog No:107177 (CRP Antibody) at dilution of 1:500. Horseradish peroxidase conjugated protein A was used for signal developing instead of secondary antibody.

  • Background
    C-reactive protein (CRP) is an acute-phase serum protein synthesized by the liver in response to interleukin-6 (IL-6) during inflammation. The name of CRP derives from its ability to react with the C polysaccharide of Streptococcus pneumoniae. CRP is an annular, pentameric protein that belongs to the pentraxin family of proteins. CRP displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. It is used mainly as a marker of inflammation.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"