CRH/CRF antibody

CRH/CRF antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

CRH/CRF Rabbit Polyclonal antibody. Positive IHC detected in human pancreas tissue, human pancreas cancer tissue. Positive WB detected in human brain tissue, rat brain tissue. Observed molecular weight by Western-blot: 35 kDa

ELISA, WB, IHC

Human,Mouse,Rat; other species not tested.

Corticoliberin antibody; Corticotropin releasing factor antibody; CRF antibody; CRH antibody

Rabbit IgG

This antibody was obtained by immunization of CRH/CRF recombinant protein (Accession Number: XM_017013091). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Corticotropin-releasing hormone (CRH), also called CRF or corticoliberin, is a peptide hormone and neurotransmitter involved in the stress response. It belongs to corticotropin-releasing factor family. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery.

• Chen F, Chen S, Liu S, Zhang C, Peng G. Effects of lorazepam and WAY-200070 in larval zebrafish light/dark choice test. Neuropharmacology. 95:226-33. 2015.