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Product Name
CPB1 antibody
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Description
CPB1 Rabbit Polyclonal antibody. Positive WB detected in mouse pancreas tissue, rat pancreas tissue. Positive IHC detected in human pancreas cancer tissue, human kidney tissue, human pancreas tissue. Observed molecular weight by Western-blot: 47 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
Carboxypeptidase B antibody; carboxypeptidase B1 (tissue) antibody; CPB antibody; CPB1 antibody; DKFZp779K1333 antibody; Pancreas specific protein antibody; PASP antibody; PCPB antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CPB1 recombinant protein (Accession Number: NM_001871). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
mouse pancreas tissue were subjected to SDS PAGE followed by western blot with Catalog No:109505(PASP antibody) at dilution of 1:1000
Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:109505(PASP antibody) at dilution of 1:50 (under 40x lens)
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Background
PASP(pancreas-specific protein) is also named as CPB1, CPB, PCPB and belongs to the peptidase M14 family. This protein modulates the plasminogen system both in the matrix and on the cell surface, thus leading to the inhibition of endothelial cell movement and tube formation. It is initially described as a pancreatic metallocarboxypeptidase and is a marker for acute pancreatitis(PMID:19717511). The deduced 416-amino acid preproenzyme has a 15-amino acid signal peptide and a 95-amino acid activation peptide.
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