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COX7B antibody

Cat.#: 109500

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Special Price 239.0 USD

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Product Information

  • Product Name
    COX7B antibody
  • Documents
  • Description
    COX7B Rabbit Polyclonal antibody. Positive IHC detected in human lymphoma tissue. Positive WB detected in human skeletal muscle tissue, human brain tissue, human liver tissue. Observed molecular weight by Western-blot: 9 kDa
  • Tested applications
    ELISA, IHC, WB
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    COX7B antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of COX7B recombinant protein (Accession Number: NM_001866). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:1000

    IHC: 1:20-1:200

  • Validations

    human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with Catalog No:109500(COX7B antibody) at dilution of 1:400

    human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with Catalog No:109500(COX7B antibody) at dilution of 1:400

    Immunohistochemical of paraffin-embedded human lymphoma using Catalog No:109500(COX7B antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human lymphoma using Catalog No:109500(COX7B antibody) at dilution of 1:100 (under 10x lens)

  • Background
    COX7B, also named as Cytochrome c oxidase subunit 7B, mitochondrial, is a 80 amino acid protein, which belongs to the cytochrome c oxidase VIIb family. COX7B protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. COX7B plays a role in proper central nervous system development in vertebrates. COX7B as a terminal enzyme in the mitochondrial respiratory chain (oxidative phosphorylation OXPHOS), catalyzing the electron transfer from reduced cytochrome c to molecule oxygen and plays a role in eye development.
  • References
    • Oliva CR, Nozell SE, Diers A. Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain. The Journal of biological chemistry. 285(51):39759-67. 2010.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"