-
Product Name
COX6B1 antibody
- Documents
-
Description
COX6B1 Rabbit Polyclonal antibody. Positive WB detected in human liver tissue, human heart tissue. Positive IHC detected in human gliomas tissue. Observed molecular weight by Western-blot: 10kd
-
Tested applications
ELISA, WB, IHC
-
Species reactivity
Human,Mouse,Rat; other species not tested.
-
Alternative names
COX VIb 1 antibody; COX6B antibody; COX6B1 antibody; COXG antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of COX6B1 recombinant protein (Accession Number: NM_001863). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
-
Validations
human liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:109494(COX6B1 antibody) at dilution of 1:400
Immunohistochemical of paraffin-embedded human gliomas using Catalog No:109494(COX6B1 antibody) at dilution of 1:50 (under 10x lens)
-
Background
COX6B1 (Cytochrome c oxidase subunit 6B1) is also named as COX6B and belongs to the cytochrome c oxidase subunit 6B family. It connects the two COX monomers into the physiological dimeric form.Defects in COX6B1 are a cause of mitochondrial complex IV deficiency (MT-C4D).
-
References
- Oliva CR, Nozell SE, Diers A. Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain. The Journal of biological chemistry. 285(51):39759-67. 2010.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"