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Product Name
Human CES2/Carboxylesterase 2 (His Tag) recombinant protein
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Description
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine.
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Protein name
Cocaine esterase
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Protein short names
ICE; CE-2; CES2A1; CES2A3; CES2; PCE-2; CARBOXYLESTERASE 2
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Uniprot ID
O00748
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Gene Name
CES2; ICE
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human CES2 isoform 1 (O00748-1) (Met 1-Leu 559) was expressed, with a C-terminal polyhistidine tag.
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Protein Species
Human
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Molecular weight
The secreted recombinant human CES2 comprises 544 amino acids with a predicted molecular mass of 60.4 kDa, as estimated in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human CES2 / Carboxylesterase-2 Protein (His Tag) SDS-PAGE
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