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Product Name
Clusterin antibody
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Description
Clusterin Rabbit Polyclonal antibody. Positive WB detected in Y79 cells. Positive IP detected in mouse brain tissue. Positive IHC detected in human tonsillitis tissue, human breast cancer tissue, human liver cancer tissue. Observed molecular weight by Western-blot: 70-80kd and 50kd
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
AAG4 antibody; Apo J antibody; APOJ antibody; ApoJalpha antibody; ApoJbeta antibody; Apolipoprotein J antibody; CLI antibody; CLU antibody; clusterin antibody; Complement cytolysis inhibitor antibody; Ku70 binding protein 1 antibody; KUB1 antibody; NA1/NA2 antibody; SGP 2 antibody; SGP2 antibody; SP 40 antibody; TRPM 2 antibody; TRPM2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Clusterin recombinant protein (Accession Number: NM_001831). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:200-1:2000
IHC: 1:20-1:200
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Validations
Y79 cells were subjected to SDS PAGE followed by western blot with Catalog No:109410(CLU antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:109410(CLU Antibody) at dilution of 1:50 (under 40x lens)
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:109410(CLU Antibody) at dilution of 1:50 (under 10x lens)
IP Result of anti-CLU (IP:Catalog No:109410, 4ug; Detection:Catalog No:109410 1:800) with mouse brain tissue lysate 4400ug.
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Background
Clusterin (Apolipoprotein J) is a 75-80 kDa heterodimeric glycoprotein produced by a wide array of tissues and found in most biologic fluids (PMID: 7648419; 11906815). It is encoded by one single gene and cleaved posttranslationally into α and β subunits prior to secretion from the cell. Many functions have been described for clusterin, including regulating apoptosis, transporting lipids, controlling cell interactions, regulating complement (PMID: 10694874).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"