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Product Name
Claudin 23 antibody
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Description
Claudin 23 Rabbit Polyclonal antibody. Positive WB detected in COLO 320 cells. Positive IHC detected in human colon cancer tissue. Observed molecular weight by Western-blot: 32 kDa
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human; other species not tested.
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Alternative names
claudin 23 antibody; CLDN23 antibody; CLDNL antibody; hCG1646163 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Claudin 23 recombinant protein (Accession Number: NM_194284). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
COLO 320 cells were subjected to SDS PAGE followed by western blot with Catalog No:109340(CLDN23 Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using Catalog No:109340(CLDN23 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using Catalog No:109340(CLDN23 Antibody) at dilution of 1:50 (under 40x lens)
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Background
Claudin 23 (CLDN23) belongs to the large claudin family of proteins, which are tetraspan transmembrane proteins of tight junctions (PMID: 12736707; 18036336). Claudins exhibit specific patterns of expression in different tissues. Human CLDN23 mRNA was expressed in germinal center B cells, placenta, stomach as well as in colon tumor (PMID: 12736707). CLDN23 has been reported as a candidate tumor suppressor gene implicated in intestinal-type gastric cancer (PMID: 12736707).
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