-
Product Name
CHCHD10 antibody
- Documents
-
Description
CHCHD10 Rabbit Polyclonal antibody. Positive WB detected in mouse heart tissue, mouse brain tissue. Positive IP detected in mouse heart tissue. Positive IHC detected in human heart tissue. Positive IF detected in A431 cells. Observed molecular weight by Western-blot: 14 kDa
-
Tested applications
ELISA, WB, IHC, IF, IP
-
Species reactivity
Human, Mouse; other species not tested.
-
Alternative names
C22orf16 antibody; CHCHD10 antibody; N27C7 4 antibody; Protein N27C7 4 antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of CHCHD10 recombinant protein (Accession Number: NM_213720). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
IHC: 1:20-1:200
IF: 1:10-1:100
-
Validations
mouse heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:109211(CHCHD10 Antibody) at dilution of 1:600
Immunofluorescent analysis of A431 cells using Catalog No:109211(CHCHD10 Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunohistochemistry of paraffin-embedded human heart tissue slide using Catalog No:109211(CHCHD10 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human heart tissue slide using Catalog No:109211(CHCHD10 Antibody) at dilution of 1:50 (under 40x lens)
IP Result of anti-CHCHD10 (IP:Catalog No:109211, 4ug; Detection:Catalog No:109211 1:600) with mouse heart tissue lysate 4000ug.
-
Background
CHCHD10 is a mitochondrial protein that is enriched at cristae junctions in the intermembrane space and is likely involved in mitochondrial genome stability and maintenance of cristae junctions. Mutations in CHCHD10 have recently been described as a cause of frontotemporal dementia (FTD) comorbid with amyotrophic lateral sclerosis (ALS).
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"