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Product Name
CFP antibody
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Description
CFP Rabbit Polyclonal antibody. Positive IHC detected in human spleen tissue. Positive WB detected in Jurkat cells. Observed molecular weight by Western-blot: 50 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
BFD antibody; CFP antibody; Complement factor P antibody; complement factor properdin antibody; PFC antibody; PFD antibody; PROPERDIN antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CFP recombinant protein (Accession Number: NM_002621). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IHC: 1:20-1:200
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:109200(CFP Antibody) at dilution of 1:300
Immunohistochemistry of paraffin-embedded human spleen tissue slide using Catalog No:109200(CFP Antibody) at dilution of 1:50 (under 40x lens)
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Background
CFP, also named as Properdin or CFP, is a 469 amino acid protein, which contains 7 TSP type-1 domains. CFP as secreted protein is a positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Properdin deficiency poses a significant risk for severe meningococcal infections (PMID: 22229731). Properdin may be novel biomarker for future risk of type 2 diabetes (PMID: 22338105).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"