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Product Name
CETP antibody
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Description
CETP Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue, human brain tissue, Transfected HEK-293 cells. Observed molecular weight by Western-blot: 66-75kd
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Tested applications
ELISA, WB
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
CETP antibody; HDLCQ10 antibody; Lipid transfer protein I antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CETP recombinant protein (Accession Number: NM_000078). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
WB result of Catalog No:109196.
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:109196(CETP antibody) at dilution of 1:600
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Background
Cholesteryl ester transfer protein (CETP) is a plasma glycoprotein which transfers cholesteryl esters, triglycerides, and phospholipids between lipoproteins. In plasma, CETP is mainly associated with HDL particles and catalyzes the transfer of cholesteryl esters from HDL to apolipoprotein (apo) B-containing plasma lipoproteins. Low plasma concentrations of high-density lipoprotein-cholesterol (HDL-C) have long been recognized as a major, independent cardiovascular disease (CVD) risk factor. It demonstrated that altered level of plasma CETP was associated with the increased risk of CVD. (17991755, 23477743)
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References
- Liu M, Chen Y, Zhang L. Regulation of Hepatic Cholesteryl Ester Transfer Protein Expression and Reverse Cholesterol Transport by Inhibition of DNA Topoisomerase II. The Journal of biological chemistry. 290(23):14418-29. 2015.
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