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Product Name
CES3 antibody
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Description
CES3 Rabbit Polyclonal antibody. Positive IHC detected in human colon cancer tissue. Positive WB detected in HeLa cells, human liver tissue. Observed molecular weight by Western-blot: 60-62kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
carboxylesterase 3 antibody; CES3 antibody; ES31 antibody; FLJ21736 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CES3 recombinant protein (Accession Number: NM_001185177). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:109194(CES3 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human colon cancer using Catalog No:109194(CES3 antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human colon cancer using Catalog No:109194(CES3 antibody) at dilution of 1:100 (under 40x lens)
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Background
CES3 is involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. It is expressed in liver, colon and small intestine. This antibody recognizes both isoforms with MW 60-62 kDa and 24 kDa.
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References
- Galligan JJ, Fritz KS, Tipney H. Profiling impaired hepatic endoplasmic reticulum glycosylation as a consequence of ethanol ingestion. Journal of proteome research. 10(4):1837-47. 2011.
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