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Product Name
CEP152 antibody
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Description
CEP152 Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue. Positive IP detected in mouse brain tissue. Observed molecular weight by Western-blot: 110 kDa
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Tested applications
ELISA, IP, WB
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
centrosomal protein 152kDa antibody; Centrosomal protein of 152 kDa antibody; CEP152 antibody; KIAA0912 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_014985). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IP: 1:200-1:2000
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Validations
IP Result of anti-CEP152 (IP:Catalog No:109266, 3ug; Detection:Catalog No:109266 1:500) with mouse brain tissue lysate 9500ug.
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:109266(CEP152 Antibody) at dilution of 1:300
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Background
CEP152, also named as KIAA0912, is a regulator of genomic integrity and cellular response to DNA damage acting through ATR-mediated checkpoint signaling. It is necessary for centrosome duplication. CEP152 functions as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, two molecules involved in centriole formation. CEP152, ATR and CENPJ control cellular responses to DNA damage. CEP152 has some isoforms woth MW 189 kDa, 152 kDa, 110 kDa and 66 kDa.
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