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CDK6 antibody

Cat.#: 109166

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Special Price 239.0 USD

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Product Information

  • Product Name
    CDK6 antibody
  • Documents
  • Description
    CDK6 Rabbit Polyclonal antibody. Positive IP detected in Jurkat cells. Positive WB detected in Jurkat cells, C6 cells, K-562 cells. Observed molecular weight by Western-blot: 37-40 kDa
  • Tested applications
    ELISA, WB, IP
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    CDK6 antibody; Cell division protein kinase 6 antibody; cyclin dependent kinase 6 antibody; PLSTIRE antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of CDK6 recombinant protein (Accession Number: BC027989). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IP: 1:200-1:2000

  • Validations

    Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:109166(CDK6 antibody) at dilution of 1:2000

    Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:109166(CDK6 antibody) at dilution of 1:2000

    IP Result of anti-CDK6 (IP:Catalog No:109166, 4ug; Detection:Catalog No:109166 1:700) with Jurkat cells lysate 3200ug.

    IP Result of anti-CDK6 (IP:Catalog No:109166, 4ug; Detection:Catalog No:109166 1:700) with Jurkat cells lysate 3200ug.

  • Background
    CDK6(Cyclin-dependent kinase 6) is involved in initiation and maintenance of cell cycle exit during cell differentiation and it prevents cell proliferation and regulates negatively cell differentiation, but is required for the proliferation of specific cell types.The range of the molecular weight is 34-50 KDa.
  • References
    • Li H, Zhou F, Du W. Knockdown of asparagine synthetase by RNAi suppresses cell growth in human melanoma cells and epidermoid carcinoma cells. Biotechnology and applied biochemistry. 2015.
    • Lin Z, Xiong L, Zhou J. γ-Glutamylcyclotransferase Knockdown Inhibits Growth of Lung Cancer Cells Through G0/G1 Phase Arrest. Cancer biotherapy & radiopharmaceuticals. 30(5):211-6. 2015.
    • Meng D, Chen Y, Yun D. High expression of N-myc (and STAT) interactor predicts poor prognosis and promotes tumor growth in human glioblastoma. Oncotarget. 6(7):4901-19. 2015.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"