CDCA7L Polyclonal Antibody

Cat.#: 162664

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Product Information

  • Product Name
    CDCA7L Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to CDCA7L
  • Tested applications
    WB
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    CDCA7L antibody; JPO2 antibody; R1 antibody; RAM2 antibody; cell division cycle associated 7 like antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CDCA7L (NP_061189.2).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:200 - 1:2000
  • Validations

    Western blot - CDCA7L Polyclonal Antibody

    Western blot - CDCA7L Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using CDCA7L antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.

  • Background
    Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"