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Product Name
CDC23 antibody
- Documents
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Description
CDC23 Rabbit Polyclonal antibody. Positive WB detected in K-562 cells, HeLa cells. Observed molecular weight by Western-blot: 49 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
ANAPC8 antibody; APC8 antibody; CDC23 antibody; Cyclosome subunit 8 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CDC23 recombinant protein (Accession Number: BC005258). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
K-562 cells were subjected to SDS PAGE followed by western blot with Catalog No:109095(CDC23 Antibody) at dilution of 1:600
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Background
CDC23(cell division cycle protein 23 homolog) is also named as ANAPC8 and belongs to the APC8/CDC23 family. It is a subunit of the anaphase-promoting complex (APC), which functions at the metaphase-to-anaphase transition of the cell cycle and is regulated by spindle checkpoint proteins. It can be phosphorylated and the phosphorylation on Thr-562 occurs specifically during mitosis(PMID:19690332). It has 3 isoforms produced by alternative splicing with the molecular weight of 69 kDa, 17 kDa and 56 kDa.
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