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Product Name
CD8b antibody
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Description
CD8b Rabbit Polyclonal antibody. Positive WB detected in HEK-293 cells, HepG2 cells. Observed molecular weight by Western-blot: 37-43 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
CD8 antibody; CD8b antibody; CD8b molecule antibody; CD8B1 antibody; Leu2 antibody; Ly3 antibody; LYT3 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CD8b recombinant protein (Accession Number: NM_172213). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:109146(CD8B antibody) at dilution of 1:300
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Background
CD8b is the beta chain of CD8, a transmembrane glycoprotein that is predominantly expressed on the surface of cytotoxic T cells, and can also be found on natural killer cells, cortical thymocytes, and dendritic cells. CD8 serves as a co-receptor for the T cell receptor (TCR). Both CD8 and TCR recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 plays a role in T cell development and activation of mature T cells.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"