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Product Name
CD68 antibody
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Description
CD68 Mouse Monoclonal antibody. Positive FC detected in RAW 264.7 cells. Positive IHC detected in human liver tissue, human tonsillitis tissue.
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Tested applications
ELISA, IHC, FC
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
CD68 antibody; CD68 molecule antibody; DKFZp686M18236 antibody; GP110 antibody; Macrosialin antibody; SCARD1 antibody
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Isotype
Mouse IgG1
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Preparation
This antibody was obtained by immunization of CD68 recombinant protein (Accession Number: NM_001251). Purification method: Protein G purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
IHC: 1:20-1:200
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Validations
Immunohistochemistry of paraffin-embedded human liver tissue slide using (CD68 Antibody) at dilution of 1:200 (under 10x lens)
Immunohistochemistry of paraffin-embedded human liver tissue slide using (CD68 Antibody) at dilution of 1:200 (under 40x lens)
1X10^6 RAW 264.7 cells were stained with 0.2ug CD68 antibody (Catalog No:107139, red) and control antibody (blue). Fixed with 4% PFA blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Mouse IgG(H+L) with dilution 1:1500.
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Background
CD68 is a type I transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It belongs to the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. CD68 is also a member of the scavenger receptor family. It may play a role in phagocytic activities of tissue macrophages.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"