CD47 antibody

CD47 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

CD47 Mouse Monoclonal antibody. Positive WB detected in SKOV-3 cells, HT-1080 cells, HUVEC cells. Observed molecular weight by Western-blot: 55 kDa

ELISA, WB

Human; other species not tested.

CD47 antibody; CD47 molecule antibody; IAP antibody; Integrin assOCiated protein antibody; LeukOCyte surface antigen CD47 antibody; MER6 antibody; OA3 antibody; Protein MER6 antibody

Mouse IgG2b

This antibody was obtained by immunization of CD47 recombinant protein (Accession Number: NM_198793). Purification method: Protein A purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

CD47, also known as integrin-associated protein (IAP), is a member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. CD47 is heavily glycosylated and widely expressed by hematopoietic and nonhematopoietic cells. CD47 interacts with several membrane integrins and also acts a receptor for thrombospondin (THBS1). It is involved in a range of cellular processes, including apoptosis, proliferation, adhesion, and migration. CD47 also functions as a ligand for signal regulatory protein-α (SIRPα). Upon binding CD47, SIRPα initiates a signaling cascade that results in the inhibition of phagocytosis.