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Product Name
CD24 antibody
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Description
CD24 Rabbit Polyclonal antibody. Positive WB detected in MCF7 cells, Jurkat cells, mouse spleen tissue, Raji cells. Observed molecular weight by Western-blot: 45-50 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
CD24 antibody; CD24 molecule antibody; CD24A antibody; FLJ22950 antibody; FLJ43543 antibody; Signal transducer CD24 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CD24 recombinant protein (Accession Number: BC007674). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
MCF7 cells were subjected to SDS PAGE followed by western blot with Catalog No:109012(CD24 antibody) at dilution of 1:500
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Background
CD24 (known as heat stable antigen) is a small highly glycosylated GPI-linked sialoprotein. It is normally expressed at the surface of most B lymphocytes and differentiating neuroblasts, and it is also up-regulated in a wide variety of cancers. Studies have shown that CD24 functions in the regulation of B-cell apoptosis, leukocyte signal transduction, and leukocyte adhesion. Since it is highly glycosylated, the apparent molecular weight of CD24 could be variable, ranging from 30 kDa to 70 kDa. (Ref: Akihiko Sano, MD., 2009)
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References
- Yang CF, Peng LX, Huang TJ. Cancer stem-like cell characteristics induced by EB virus-encoded LMP1 contribute to radioresistance in nasopharyngeal carcinoma by suppressing the p53-mediated apoptosis pathway. Cancer letters. 344(2):260-71. 2014.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"