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Product Name
Rat CD226/DNAM-1 (His Tag) recombinant protein
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Description
The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD226, also known as PTA1 or DNAM-1, is a member of the immunoglobulin superfamily containing 2 Ig-like domains of the V-set. High rate of CD226 (Cluster of Differentiation 226) is found on the surface of natural killer cells, platelets, monocytes and a subset of T cells. CD226 have binding sites with CD112 and CD155 and mediate cellular adhesion to other cells containing its ligands.
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Protein name
CD226 antigen (Predicted), isoform CRA_b
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Protein short names
CD226; BC051526; PTA1; DNAM1; DNAM-1; TLISA1
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Uniprot ID
D3ZS97
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Gene Name
Cd226; Cd226_predicted; rCG_20583
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the rat Cd226 (NP_001100840.1) (Met1-Ile265) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Rat
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Molecular weight
The recombinant rat Cd226 consists 245 amino acids and predicts a molecular mass of 28 kDa.
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Purity
> 95 % as determined by SDS-PAGE.
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Validations
Rat CD226 / DNAM-1 Protein (His Tag)
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