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Product Name
CD138/Syndecan-1 antibody
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Description
CD138/Syndecan-1 Mouse Monoclonal antibody. Positive WB detected in MCF7 cells. Positive IHC detected in human tonsil tissue, human colon tissue. Observed molecular weight by Western-blot: 140 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
CD138 antibody; SDC antibody; SDC1 antibody; SYND1 antibody; syndecan antibody; syndecan 1 antibody
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Isotype
Mouse IgG2a
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Preparation
This antibody was obtained by immunization of CD138/Syndecan-1 recombinant protein (Accession Number: NM_002997). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
MCF7 cells were subjected to SDS PAGE followed by western blot with Catalog No:107043(SDC1,CD138 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human tonsil using Catalog No:107043(SDC1,CD138 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human tonsil using Catalog No:107043(SDC1,CD138 antibody) at dilution of 1:50 (under 40x lens)
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Background
Syndecan-1 (SDC1), also named CD138, is an integral membrane protein. It participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. It is a heparan sulfate proteoglycan expressed on the surface of, and actively shed by, myeloma cells. Altered syndecan-1 expression has been detected in several different tumor types. SDC1 was regarded as a useful marker for labeling normal and neoplastic plasma cells and plasmacytoid lymphomas.
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