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Product Name
CD109 antibody
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Description
CD109 Mouse Monoclonal antibody. Positive WB detected in Jurkat cells. Observed molecular weight by Western-blot: 162 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
CD109 antibody; CD109 antigen antibody; CD109 molecule antibody; CPAMD7 antibody; DKFZp762L1111 antibody; FLJ38569 antibody; FLJ41966 antibody; p180 antibody; Platelet specific Gov antigen antibody; r150 antibody; RP11 525G3.1 antibody
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Isotype
Mouse IgG1
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: XM_005248659). Purification method: Caprylic acid/ammonium sulfate precipitation.
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Clonality
Monoclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
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Validations
Jurkat cells were subjected to SDS PAGE followed by western blot with Catalog No:107038(CD109 Antibody) at dilution of 1:4000
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Background
CD109, also named as CPAMD7, is a member of the alpha2-macroglobulin/complement superfamily. It is a glycosylphosphatidylinositol (GPI)-linked cell surface glycoprotein of approximately 170kd which is found on the cell surface of platelets, activated T-cells, and endothelial cells. CD109 binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta). CD109 has been identified as part of the TGF-beta receptor system in human keratinocytes. Up regulation of CD109 expression has been observed in several different types of tumor. Multiple transcript variants encoding different isoforms have been found for CD109. The antibody can recognize all these 4 isoforms.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"