Product Name

CCR7 antibody

Documents

Description

CCR7 Rabbit Polyclonal antibody. Positive FC detected in K-562 cells. Positive IHC detected in human tonsillitis tissue.

Tested applications

ELISA, IHC, FC

Species reactivity

Human; other species not tested.

Alternative names

BLR2 antibody; C C chemokine receptor type 7 antibody; C C CKR 7 antibody; CC CKR 7 antibody; CCR 7 antibody; CCR7 antibody; CD197 antibody; CDw197 antibody; CMKBR7 antibody; EBI1 antibody; EVI1 antibody; MIP 3 beta receptor antibody

Isotype

Rabbit IgG

Preparation

This antibody was obtained by immunization of Peptide (Accession Number: NM_001838). Purification method: Antigen affinity purified.

Clonality

Polyclonal

Formulation

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage instructions

Store at -20℃. DO NOT ALIQUOT

Applications

Recommended Dilution:

IHC: 1:20-1:200

Validations

Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:109078(CCR7 Antibody) at dilution of 1:50 (under 10x lens)

Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:109078(CCR7 Antibody) at dilution of 1:50 (under 40x lens)

1X10^6 K-562 cells were stained with 0.2ug CCR7 antibody (Catalog No:109078, red) and control antibody (blue). Fixed with 90% MeOH blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1000.

Background

C-C chemokine receptor type 7 (CCR7) , which belongs to the G-protein coupled receptor 1 family, is also a receptor for the MIP-3-beta chemokine, and probablely acts as mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. CCR7 is specially expressed in various lymphoid tissues and activated B- and T-lymphocytes, and can be strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.

CCR7 antibody

Product Information

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