CCNL1 antibody

CCNL1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

CCNL1 Rabbit Polyclonal antibody. Positive WB detected in COLO 320 cells, MCF7 cells, PC-3 cells. Observed molecular weight by Western-blot: 46kd

ELISA, WB

Human,Mouse,Rat; other species not tested.

ania 6a antibody; BM 001 antibody; CCNL1 antibody; Cyclin L antibody; cyclin L1 antibody; PRO1073 antibody; UNQ530/PRO1073 antibody

Rabbit IgG

This antibody was obtained by immunization of CCNL1 recombinant protein (Accession Number: NM_020307). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

CCNL1, also named as Cyclin-L1, contains a RS region and belongs to the cyclin family. CCNL1 localizes in the nucleus speckle and is Overexpressed in primary tumors of head and neck squamous cell carcinomas (HNSCC). CCNL1 as transcriptional regulator participates in regulating the pre-mRNA splicing process. It is seems to be involved in the regulation of RNA polymerase II (pol II). CCNL1 functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. It may be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). The calculated molecular weight of CCNL1 is about 55-60 kDa, but we detected a 40-50 kDa isoform by western blotting.