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Product Name
CCKBR-specific antibody
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Description
CCKBR-specific Rabbit Polyclonal antibody. Positive IF detected in BxPC-3 cells. Positive WB detected in BxPC-3 cells, human stomach tissue, SGC-7901 cells. Observed molecular weight by Western-blot: 64 kDa or 50 kDa
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Tested applications
ELISA, WB, IF
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Species reactivity
Human; other species not tested.
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Alternative names
CCK B antibody; CCK B receptor antibody; CCK BR antibody; CCK2 R antibody; CCK2R antibody; CCKBR antibody; CCKRB antibody; Cholecystokinin 2 receptor antibody; cholecystokinin B receptor antibody; GASR antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_176875). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IF: 1:10-1:100
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Validations
BxPC-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:108998(CCKBR-specific antibody) at dilution of 1:300
Immunofluorescent analysis of BxPC-3 cells using Catalog No:108998(CCKBR-specific Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Background
The cholecystokinin B receptor (CCKBR) is a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors.
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