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Product Name
CCKBR Polyclonal Antibody
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Description
Polyclonal antibody to CCKBR
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Tested applications
WB
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Species reactivity
Human, Mouse, Rat
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Alternative names
CCKBR antibody; CCK-B antibody; CCK2R antibody; GASR antibody; cholecystokinin B receptor antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human CCKBR
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
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Validations
Western blot - CCKBR Polyclonal Antibody
Western blot analysis of extracts of human stomach cancer tissue, using CCKBR antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Background
Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.; Isoform 2 is constitutively activated and may regulate cancer cell proliferation via a gastrin-independent mechanism.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"