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Product Name
CCBL1/KAT1 antibody
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Description
CCBL1/KAT1 Rabbit Polyclonal antibody. Positive WB detected in mouse kidney tissue, HeLa cells, L02 cells. Observed molecular weight by Western-blot: 48-50 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
CCBL1 antibody; Glutamine transaminase K antibody; GTK antibody; KAT1 antibody; KATI antibody; Kynurenine aminotransferase I antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CCBL1/KAT1 recombinant protein (Accession Number: BC013069). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
mouse kidney tissue were subjected to SDS PAGE followed by western blot with Catalog No:108956(CCBL1 Antibody) at dilution of 1:600
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Background
CCBL1 encodes kynurenine aminotransferase 1 (KAT1), a key enzyme involved in kynurenine pathway. CCBL1 catalyzes the production of kynurenic acid, a powerful endogenous excitatory amino acid receptor antagonist that is widely regarded as the potent neuroprotective agent.
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References
- Agudelo LZ, Femenía T, Orhan F. Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression. Cell. 159(1):33-45. 2014.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"