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Product Name
CBFA2T2 antibody
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Description
CBFA2T2 Rabbit Polyclonal antibody. Positive IHC detected in human gliomas. Positive WB detected in HEK-293 cells, mouse testis tissue, PC-3 cells. Observed molecular weight by Western-blot: 85kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
human, mouse, rat; other species not tested.
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Alternative names
CBFA2T2 antibody; Protein CBFA2T2 antibody; p85 antibody; ZMYND3 antibody; MTG8 like protein antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of CBFA2T2 recombinant protein (Accession Number: BC015066). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:108896(CBFA2T2 antibody) at dilution of 1:300
Immunohistochemical of paraffin-embedded human gliomas using Catalog No:108896(CBFA2T2 antibody) at dilution of 1:50 (under 10x lens)
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Background
Core-binding factor, runt domain, alpha subunit 2, translocated to 2(CBFA2T2) belongs to a family of ubiquitously expressed transcriptional repressors that interact with transcription factors bound to promoters of target genes and with histone deacetylases (HDACs) critical for enforcement of repressor function.CBFA2T2, also named as MTGR1 or EHT, is an 85-kDa phosphoprotein. It can bind AML1-MTG8 fusion protein in acute myeloid leukemia. The binding leads to an enhancement of cell proliferation mediated in a murine myeloid model.
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