Cathepsin V antibody

Cat.#: 108894

Size:

Special Price 239.0 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Cathepsin V antibody
  • Documents
  • Description
    Cathepsin V Rabbit Polyclonal antibody. Positive WB detected in human testis tissue, Jurkat cells, MCF-7 cells, mouse testis tissue. Observed molecular weight by Western-blot: 37-39kd,30kd
  • Tested applications
    ELISA, WB
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    cathepsin L2 antibody; Cathepsin U antibody; Cathepsin V antibody; CATL2 antibody; CTSL2 antibody; CTSU antibody; CTSV antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Cathepsin V recombinant protein (Accession Number: NM_001333). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

  • Validations

    human testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:108894(CTSL2 antibody) at dilution of 1:800

    human testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:108894(CTSL2 antibody) at dilution of 1:800

  • Background
    Cathepsin V is a lysosomal cysteine protease which has an important role in corneal physiology.Cathepsin V was found to be differentially expressed in relation to pigmentary skin backgrounds, and was about 7.5-folds higher in keratinocytes from lightly pigmented, relative to darkly pigmented skins. It is expressed in primary keratinocytes, melanocytes, and HaCaT keratinocytes, but not in primary fibroblasts. The purified cathepsin L2 was a high molecular weight proteinase of about 78 kDa, but it was unstable to SDS and reducing conditions, which dissociated parts of the proteinase into 66 kDa, 31 kDa and 26 kDa fragments(Food Chemistry,Volume11,Issue4,879-886) and it can form a complex of 70 kDa with an unidentified subunit(PMID:1930136).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"