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Product Name
Cathepsin F antibody
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Description
Cathepsin F Rabbit Polyclonal antibody. Positive IHC detected in human prostate cancer tissue, human heart tissue, human stomach cancer tissue, mouse heart tissue, mouse liver tissue. Positive WB detected in Transfected HEK-293 cells.
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
Cathepsin F antibody; CATSF antibody; CTSF antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Cathepsin F recombinant protein (Accession Number: NM_003793). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:108890(CTSF antibody) at dilution of 1:100 (under 10x lens)
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:108890(CTSF Antibody) at dilution of 1:1000
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Background
CTSF(Cathepsin F) is a member of the papain family of cysteine proteases. These enzymes represent a major component of the lysosomal proteolytic system. They are synthesized as inactive precursors consisting of a signal sequence, a propeptide, and a catalytically active mature region. Cathepsins are routed to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The deduced 484-amino acid cathepsin F protein has a signal sequence and potential glycosylation sites.
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References
- Saghizadeh M, Kramerov AA, Yaghoobzadeh Y. Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes. Brain research bulletin. 81(2-3):262-72. 2010.
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